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Advances in Type 1 Diabetes Science and Tech

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Advances in Type 1 Diabetes Science and Tech


Type 1 Diabetes Science Is Having a Moment

Living with type 1 diabetes today is leaps and bounds easier than it was decades ago. Things are only getting better

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This article is part of “Innovations In: Type 1 Diabetes,” an editorially independent special report that was produced with financial support from Vertex.

A little more than a century ago a diagnosis of type 1 diabetes was a death sentence. Today, thanks to extraordinary scientific progress, many people with type 1 diabetes—especially in developed countries—can enjoy long, healthy lives. I’m profoundly grateful that my older son, now 16, was born into this era of possibility. His diagnosis in 2020 came at a time when innovation and advocacy had transformed what it meant to live with this chronic autoimmune disease. I’m excited to share this Innovations In special report, in which we explore the remarkable advances reshaping the landscape of type 1 diabetes research and care.

Science journalist Carrie Arnold tells the stories of visionary entrepreneurs working toward an artificial pancreas—a closed-loop system that seamlessly integrates insulin pumps and glucose monitors to mimic the function of healthy beta cells. For many, this breakthrough feels like a cure.


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Yet the pursuit of a true cure continues. Health journalist Tara Haelle delves into promising options, including beta cell transplants that would eliminate the need for immunosuppressive drugs. She also highlights the monoclonal antibody teplizumab, approved in 2022, which can delay the onset of symptomatic type 1 diabetes by five years or more in some people—a milestone in preventive medicine.

As the science races forward, the number of type 1 diabetes cases is surging. Statistical visualizations by data journalist Miriam Quick and senior graphics editor Jen Christiansen illustrate this troubling trend and expose the stark disparities in care. In wealthy nations such as the United Arab Emirates, a child diagnosed with type 1 diabetes may live nearly a full life. In contrast, a child in Niger could lose up to 50 years compared with the national average.

Associate editor Lauren J. Young introduces us to five exceptional individuals working to close these gaps—among them a radiology specialist who joined forces with fellow mothers to distribute insulin and establish education outreach across Venezuela, as well as clinicians trying to ease distress over diabetes and improve mental health. Their stories are deeply moving.

Health reporter Liz Szabo explores the strides in preventing or halting diabetic retinopathy, the leading cause of blindness in working-age adults. Science journalist Rachel Nuwer describes advances in genetic screening to identify kids at high risk of developing type 1 diabetes. That information could become life-altering as new treatments emerge.

Although managing type 1 diabetes will continue to be a 24/7 endeavor for now, I have realistic hope that a cure will emerge in my son’s lifetime.

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